Dr. Sankarganesh Arunachalam?s research focuses on Cardiovascular Adverse Drug Reactions. His primary interest is in understanding how the drug Doxorubicin leads to complications, particularly cardiomyopathy. This drug?s clinical use is restricted due to its many adverse effects, including cardiomyopathy. Dr. Arunachalam discovered that Doxorubicin dysregulates the PPAR family, revealing new insights. His findings also indicate that Doxorubicin inhibits adipocyte differentiation, contributing to weight loss during chemotherapy. His team identified that PPARγ inhibition reduces adipose tissue, affecting spermatogenesis. Their research suggests that Doxorubicin induces a type 2 diabetic condition through adipose tissue inflammation. Dr. Arunachalam?s work explores two mechanisms: dysregulation of cardiac energetics and impairment of cardiac progenitor cells. His research has been supported by two grants from SERB, Government of India, and one from DST, Government of India.
Chonbuk National University, South Korea
University of Madras
University of Madras
Date Of Publication: 27-Sep-2024
Name of Journal: Journal Of Biochemical And Molecular Toxicology
Volume No/Issue No/Page No: 38/10/ -
Date Of Publication: 25-Apr-2023
Name of Journal: 3 Biotech
Volume No/Issue No/Page No: // -
Date Of Publication: 06-Aug-2022
Name of Journal: Journal of Applied Toxicology
Volume No/Issue No/Page No: // -
Date Of Publication: 14-Feb-2022
Name of Journal: Cardiovascular Toxicology
Volume No/Issue No/Page No: // -
Date Of Publication: 12-Feb-2022
Name of Journal: Biointerface Research in Applied Chemistry
Volume No/Issue No/Page No: 13/1/1 - 13
Date Of Publication: 02-Feb-2022
Name of Journal: Biointerface Research in Applied Chemistry
Volume No/Issue No/Page No: 13/1/1 - 18
Date Of Publication: 12-Dec-2021
Name of Journal: Biointerface Research in Applied Chemistry
Volume No/Issue No/Page No: // -
Date Of Publication: 02-Nov-2021
Name of Journal: Scientific Reports
Volume No/Issue No/Page No: 11/1/21488 -
Date Of Publication: 18-Apr-2021
Name of Journal: Reproductive Toxicology
Volume No/Issue No/Page No: // -
Date Of Publication: 02-Jan-2021
Name of Journal: 3 Biotech
Volume No/Issue No/Page No: 11/15/1 - 13
Date Of Publication: 02-Jan-2021
Name of Journal: Journal of Porous Materials
Volume No/Issue No/Page No: 28/1/515 - 527
Date Of Publication: 19-Oct-2020
Name of Journal: 3 Biotech
Volume No/Issue No/Page No: 10/11/1 - 10
Date Of Publication: 13-Feb-2020
Name of Journal: Frontiers in Aging Neuroscience
Volume No/Issue No/Page No: 12/1/1 - 12
Date Of Publication: 16-Jul-2019
Name of Journal: Chemical Research in Toxicology
Volume No/Issue No/Page No: 33/1/312 - 323
Date Of Publication: 19-Feb-2019
Name of Journal: Medical Hypotheses
Volume No/Issue No/Page No: 124/1/121 - 124
Date Of Publication: 20-Oct-2017
Name of Journal: European Journal of Pharmacology
Volume No/Issue No/Page No: 818/1/241 - 253
Date Of Publication: 06-Oct-2017
Name of Journal: Asian Pacific Journal of Tropical Biomedicine
Volume No/Issue No/Page No: 7/11/1041 - 1045
Date Of Publication: 29-Sep-2015
Name of Journal: Journal of the Science of Food and Agriculture
Volume No/Issue No/Page No: 96/9/3063 - 3068
Date Of Publication: 23-Jan-2014
Name of Journal: Pesticide Biochemistry and Physiology
Volume No/Issue No/Page No: 109/1/18 - 33
Date Of Publication: 07-Nov-2013
Name of Journal: Journal of Pharmaceutical Innovation
Volume No/Issue No/Page No: 8/1/265 - 275
Date Of Publication: 20-Mar-2013
Name of Journal: Colloids and Surfaces B: Biointerfaces
Volume No/Issue No/Page No: 109/1/20 - 24
Date Of Publication: 13-Mar-2013
Name of Journal: Colloids and Surfaces B: Biointerfaces
Volume No/Issue No/Page No: 108/1/185 - 190
Date Of Publication: 07-Dec-2012
Name of Journal: FEBS Letters
Volume No/Issue No/Page No: 587/1/105 - 110
Date Of Publication: 12-Apr-2012
Name of Journal: Toxicology Mechanisms and Methods
Volume No/Issue No/Page No: 22/7/540 - 546
Date Of Publication: 13-Oct-2011
Name of Journal: Medical Hypotheses
Volume No/Issue No/Page No: 78/1/218 - 220
Date Of Publication: 21-Aug-2011
Name of Journal: Journal of Natural Medicines
Volume No/Issue No/Page No: 66/1/149 - 157
Date Of Publication: 08-May-2009
Name of Journal: Biochemical and Biophysical Research Communications
Volume No/Issue No/Page No: 385/1/38 - 43
Type of the Program: Seminar
Role: Participant
Title:
Date: 2024-05-23
Organising Institution: Kalasalingam Academy of Research and Education
Level: Institutional
Type of the Program: Seminar
Role: Participant
Title:
Date: 2024-04-30
Organising Institution: European Toxicology Society
Level: International
Type of the Program: Conference
Role: Moderator/Chair
Title:
Date: 2024-03-21
Organising Institution: Christ University
Level: International
Type of the Program: Conference
Role: Participant
Title:
Date: 2023-11-07
Organising Institution: Laboratory Animal Scientists' Association, India
Level: International
Type of the Program: Conference
Role: Participant
Title:
Date: 2023-10-30
Organising Institution: Reva University, Bengaluru
Level: International
Name of Student: ZUBIN PHILIP
Institutions: Christ University
Month & Year: August 2024
Investigator(s) :
Sponsors: Science and Engineering Research Board
Investigator(s) :
Sponsors: Science and Engineering Research Board
Investigator(s) :
Sponsors: Department of Science and Technology
Name of the Workshop/FDP/Training Programme: Advancements of 3R's in Biomedical Research, Laboratory Animal Science and Welfare: International Perspectives
Name of the Organiser: Laboratory Animal Scientists' Association, India
Level: International
Role: Participant
Date: 2023-11-06 00:00:00
Name of the Workshop/FDP/Training Programme: Faculty Orientation Program
Name of the Organiser: CHRIST (Deemed to be University)
Level: Institutional
Role: Participant
Date: 2023-09-19 00:00:00
Name of the Workshop/FDP/Training Programme: Workshop Series on Enhancing Mentoring Skills
Name of the Organiser: CHRIST University
Level: Regional
Role: Participant
Date: 2023-08-16 00:00:00
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